Highlights
- •Tranexamic Acid reduces intraoperative blood loss in meningioma surgery.
- •Tranexamic Acid has no affect on blood transfusion requirement or postoperative outcomes in meningioma surgery.
Abstract
Keywords
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- CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014-2018.Neuro Oncol. 2021; 23 (PMID: 34608945; PMCID: PMC8491279): iii1-iii105https://doi.org/10.1093/neuonc/noab200
Goldbrunner R, Stavrinou P, Jenkinson MD, Sahm F, Mawrin C, Weber DC, Preusser M, Minniti G, Lund-Johansen M, Lefranc F, Houdart E, Sallabanda K, Le Rhun E, Nieuwenhuizen D, Tabatabai G, Soffietti R, Weller M. EANO guideline on the diagnosis.
- Predictive factors for fever and sepsis following percutaneous nephrolithotomy: A review of 580 patients.Urol Ann. 2017; 9: 230
- Meningioma.Curr Neurol Neurosci Rep. 2013; 13: 337
- Role of tranexamic acid in reducing intraoperative blood loss and postoperative edema and ecchymosis in primary elective rhinoplasty: A systematic review and meta-analysis.JAMA Facial Plast Surg. 2019; 21: 191-198https://doi.org/10.1001/jamafacial.2018.1737. PMID: 30605219; PMCID: PMC6537831
- Tranexamic acid: a review of its use in surgery and other indications.Drugs. 1999; 57 (PMID: 10400410): 1005-1032https://doi.org/10.2165/00003495-199957060-00017
- Clinical outcome and risk factors of red blood cell transfusion in patients undergoing elective primary meningioma resection.Cancers (Basel). 2021; 13: 3601https://doi.org/10.3390/cancers13143601. PMID: 34298814; PMCID: PMC8307823
Excellence, N. (2022). TRANEXAMIC ACID | Drug | BNF content published by NICE. Retrieved 5 January 2022, from https://bnf.nice.org.uk/drug/tranexamic-acid.html.
- Characterization and prognostic implications of significant blood loss during intracranial meningioma surgery.Transl Cancer Res. 2016; 5: 797-804
- Tranexamic acid in trauma: how should we use it?.J Thromb Haemost. 2015; 13 (PMID: 26149023): S195-S199https://doi.org/10.1111/jth.12878
- Effect of tranexamic acid on intraoperative blood loss and transfusion requirements in patients undergoing excision of intracranial meningioma..J Clin Neurosci. 2017; 41 (Epub 2017 Mar 7. PMID: 28283245): 132-138https://doi.org/10.1016/j.jocn.2017.02.053
- The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health Technol Assess. 2013 Mar; 17: 1-79https://doi.org/10.3310/hta17100. PMID: 23477634; PMCID: PMC4780956
- Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.Anesthesiology. 2005; 102 (PMID: 15791100): 727-732https://doi.org/10.1097/00000542-200504000-00006
- Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial.Lancet. 2018; 391: 2107-2115
Ravi GK, Panda N, Ahluwalia J, Chauhan R, Singla N, Mahajan S. Effect of tranexamic acid on blood loss, coagulation profile, and quality of surgical field in intracranial meningioma resection: A prospective randomized, double-blind, placebo-controlled study. Surg Neurol Int. 2021; 12:272. 10.25259/SNI_296_2021. PMID: 34221603; PMCID: PMC8247710.
Rebai L, Mahfoudhi N, Fitouhi N, Daghmouri MA, Bahri K. Intraoperative tranexamic acid use in patients undergoing excision of intracranial meningioma: Randomized, placebo-controlled trial. Surg Neurol Int. 2021; 12:289. 10.25259/SNI_177_2021. PMID: 34221620; PMCID: PMC8247750.
- Use of Tranexamic Acid to reduce intraoperative bleeding in craniotomy for Meningioma pateints.Asian Arch Anaesthesiol Resuscitat. 2017;
- The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.BMJ. 2021; 29n71https://doi.org/10.1136/bmj.n71. PMID: 33782057; PMCID: PMC8005924
- Rayyan — a web and mobile app for systematic reviews.Syst Rev. 2016; 5: 210https://doi.org/10.1186/s13643-016-0384-4
Deeks J, Higgins J. Statistical algorithms in review manager 5. 2010 Aug. https://training.cochrane.org/handbook/statistical-methods-revman5.
Higgins J P T, Altman D G, Gøtzsche P C, Jüni P, Moher D, Oxman A D et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials BMJ 2011; 343 :d5928 doi:10.1136/bmj.d5928.
- Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis..BMJ. 2012; 344 (PMID: 22611164; PMCID: PMC3356857): e3054https://doi.org/10.1136/bmj.e3054
- The silent risks of blood transfusion.Curr Opin Anaesthesiol. 2008; 21 (PMID: 18784496): 664-668https://doi.org/10.1097/ACO.0b013e32830f1fd1
- Transfusion-associated circulatory overload and transfusion-related acute lung injury.Am J Clin Pathol. 2021; 156 (PMID: 33822854): 529-539https://doi.org/10.1093/ajcp/aqaa279
- Strategies to minimize intraoperative blood loss during major surgery.Br J Surg. 2020 Jan; 107 (PMID: 31903592): e26-e38https://doi.org/10.1002/bjs.11393
- Postoperative central nervous system infection: incidence and associated factors in 2111 neurosurgical procedures.Clin Infect Dis. 2007; 45 (Epub 2007 May 21 PMID: 17554701): 55-59https://doi.org/10.1086/518580
- Risk factors in postoperative neurosurgical infection.A prospective study Acta Neurochir (Wien). 1992; 119 (PMID: 1481758): 80-84https://doi.org/10.1007/BF01541786
Tranexamic acid and thrombosis. Prescrire Int. 2013 Jul;22(140):182-3. PMID: 23951593.
- Patient perceptions and quality of life after colon and rectal surgery: what do patients really want?.Dis Colon Rectum. 2018; 61: 971-978https://doi.org/10.1097/DCR.0000000000001078. PMID: 29944576. = 33, 33
The COSMIC Project. COMET registration No.1508, accessible at https://comet-initiative.org/Studies/Details/1508 . This study has University of Liverpool sponsorship and ethical approval (Ref UoL001601) – 34. Date last accessed 01/06/2022.
- Measurement of intraoperative blood loss in pediatric orthopaedic patients: evaluation of a new method.J Am Acad Orthop Surg Glob Res Rev. 2018; 2: e014
World Health Organization & WHO Patient Safety. (2008). Implementation manual: WHO surgical safety checklist (first edition). World Health Organization. https://apps.who.int/iris/handle/10665/70046.
- A standardized method for calculating blood loss.Transfusion. 1997; 37 (PMID: 9354828): 1070-1074https://doi.org/10.1046/j.1537-2995.1997.371098016448.x