Highlights
- •30 percent of patients with Guillain-Barré syndrome have affected sural nerve.
- •Patients with affected sural nerve do not present worse functional prognosis with respected sural nerve.
- •Age >50 years and Hughes scale ≥3 are risk factors for presenting sural nerve affected at admission in patients with Guillaín-Barre syndrome.
Abstract
Background
Sural sparing is common in Guillain-Barré syndrome (GBS). However, one third of patients
have sural nerve compromise. Its clinical implications associated factors and short-term
prognosis are still unknown. The objective of this study is to identify if sural nerve
compromise is associated with a worse prognosis and to describe clinical and electrophysiological
characteristics in Guillain-Barré syndrome.
Materials and methods
We prospectively analyzed patients with Guillain-Barré diagnosis with vs without sural
nerve compromise. All patients underwent nerve conduction studies within the first
3 days of hospital admission. Clinical and electrophysiological characteristics were
compared between groups.
Results
174 patients were included in this study. Acute inflammatory demyelinating polyneuropathy
was the predominant variant (43.7 %). Thirty percent of patients had sural nerve involvement.
In the comparative analysis between affected vs unaffected sural groups, age ≥50 years
and Guillain-Barré disability score ≥3 demonstrated a statistically significant difference.
Regarding short-term recovery period for independent walking, there was no significant
difference. In the multivariate analysis, age ≥50 years was identified as independent
factors for sural nerve compromise on admission.
Conclusion
sural nerve compromise occurs in 30 % of patients with GBS and is not associated with
a worse functional prognosis. Age ≥50 years was identified as an independent factor
for sural nerve compromise.
Keywords
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Article info
Publication history
Accepted:
January 4,
2023
Received:
September 3,
2022
Identification
Copyright
© 2023 Elsevier Ltd. All rights reserved.
