Results of a 2-week novel robotic rehabilitation program in 18 children with prior hemispherectomy

  • Saman Hazany
    Corresponding author at: Department of Radiology, Neuroradiology Division; Keck School of Medicine, University of Southern California, 1500 San Pablo Street, Second Floor Imaging, Los Angeles, CA 90033, USA.
    Department of Neuroradiology, Keck School of Medicine, University of Southern California, 1500 San Pablo Street, Second Floor Imaging, Los Angeles, CA 90033, USA

    Rancho Los Amigos National Rehabilitation Center, 7601 Imperial Highway, Downey, CA 90242, USA
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  • Neelesh Bagrodia
    Keck School of Medicine, University of Southern California, 1975 Zonal Ave, Los Angeles, CA 90033, USA
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  • Remy Chu Jr
    Rancho Los Amigos National Rehabilitation Center, 7601 Imperial Highway, Downey, CA 90242, USA
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  • Susan Shaw
    Rancho Los Amigos National Rehabilitation Center, 7601 Imperial Highway, Downey, CA 90242, USA

    Department of Neurology, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, Suite 215, Los Angeles, CA 90089, USA
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      • Clinically meaningful and statistically significant improvements in motor function and behavior observed following a novel robotic rehabilitation two-week program in 18 patients with prior hemispherectomy.
      • Training camps enhance patient and parent confidence in task performance.
      • Rehabilitation related improvement in motor function and behavior years after hemispherectomy procedure suggest continued long-term neuroplasticity.



      Partial preservation of sensory and motor functions in the contralateral extremities after hemispherectomy is likely secondary to cortical reorganization of the remaining hemisphere and can be improved by rehabilitation. This study aims to investigate behavioral changes that may occur after a 2-week novel robotic rehabilitation program in 18 children with prior anatomic hemispherectomy. Other conventional rehabilitation methods were also reviewed and compared.


      This study examined the impact of a novel robotic rehabilitation 2-week program on 18 hemispherectomy patients (average age 14.3 ± 3.9 years; age at hemispherectomy 5.6 ± 4.5 years).


      Statistically significant improvements were seen in the six-minute walk test (29 m, p < 0.001), Canadian Occupational Performance Measure performance (1.64 points, p = 0.002) and satisfaction (2.49 points, p = 0.001), and individual perceived performance on survey (1.72 points, p = 0.042). Fifteen patients showed improvement in the upper extremity Fugl-Meyer scores with an average increase of 3 points (p = 0.006).


      This study demonstrates clinically meaningful and statistically significant improvements in motor function and behavior following a novel robotic rehabilitation two-week program.


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