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Facial emotion perception and recognition deficits in acute ischemic stroke

  • Ling Luo
    Affiliations
    Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China

    Key Laboratory of Brain Aging and Neurodegenerative Diseases, Fujian Medical University, 1 Xueyuan Road, Fuzhou 350001, PR China
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  • Xuanyu Huang
    Correspondence
    Corresponding authors at: Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China.
    Affiliations
    Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China

    Key Laboratory of Brain Aging and Neurodegenerative Diseases, Fujian Medical University, 1 Xueyuan Road, Fuzhou 350001, PR China
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  • Yingchun Xiao
    Affiliations
    Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China

    Key Laboratory of Brain Aging and Neurodegenerative Diseases, Fujian Medical University, 1 Xueyuan Road, Fuzhou 350001, PR China
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  • Ronghua Chen
    Affiliations
    Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China

    Key Laboratory of Brain Aging and Neurodegenerative Diseases, Fujian Medical University, 1 Xueyuan Road, Fuzhou 350001, PR China
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  • Erhan Yu
    Affiliations
    Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China

    Institute of Clinical Neurology, Fujian Medical University, 29 Xinquan Road, Fuzhou 350001, PR China

    Key Laboratory of Brain Aging and Neurodegenerative Diseases, Fujian Medical University, 1 Xueyuan Road, Fuzhou 350001, PR China
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  • Qilin Yuan
    Affiliations
    Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China

    Key Laboratory of Brain Aging and Neurodegenerative Diseases, Fujian Medical University, 1 Xueyuan Road, Fuzhou 350001, PR China
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  • Yun Huang
    Affiliations
    Department of Geriatric Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350001, PR China
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  • Huapin Huang
    Affiliations
    Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China

    Key Laboratory of Brain Aging and Neurodegenerative Diseases, Fujian Medical University, 1 Xueyuan Road, Fuzhou 350001, PR China
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  • Xiaochun Chen
    Affiliations
    Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China

    Institute of Clinical Neurology, Fujian Medical University, 29 Xinquan Road, Fuzhou 350001, PR China

    Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, 88 Jiaotong Road, Fuzhou 350001, PR China
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  • Author Footnotes
    1 ORCID ID: 0000-0001-9511-6986.
    Xiaodong Pan
    Correspondence
    Corresponding authors at: Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China.
    Footnotes
    1 ORCID ID: 0000-0001-9511-6986.
    Affiliations
    Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China

    Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou 350001, PR China

    Institute of Clinical Neurology, Fujian Medical University, 29 Xinquan Road, Fuzhou 350001, PR China

    Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, 88 Jiaotong Road, Fuzhou 350001, PR China

    Key Laboratory of Brain Aging and Neurodegenerative Diseases, Fujian Medical University, 1 Xueyuan Road, Fuzhou 350001, PR China

    Fujian Key Laboratory of Vascular Aging, Fujian Medical University,29 Xinquan Road, Fuzhou 350001, PR China
    Search for articles by this author
  • Author Footnotes
    1 ORCID ID: 0000-0001-9511-6986.
Published:November 09, 2022DOI:https://doi.org/10.1016/j.jocn.2022.10.002

      Highlights

      • Compared with normal control, all three groups of acute ischemic stroke (AIS) patients reported significant facial emotion perception and recognition (FEPR) deficits.
      • The FEPR deficit patterns were markedly different among left brain damage (LBD), right brain damage (RBD), and infratentorial brain damage (IBD) patients.
      • FEPR deficits were positively correlated with cognitive functions.

      Abstract

      Background

      Facial emotion perception and recognition (FEPR) deficits are the sources of disability, impaired social relationship, and reduced quality of life. Studies of unilateral acute ischemic stroke (AIS) remain controversial about FEPR deficits.

      Methods

      Clinical and neurocognitive data were collected and analyzed among normal controls (NC) and AIS patients with left brain damage (LBD), right brain damage (RBD), and infratentorial brain damage (IBD). To assess FEPR, all participants completed a localization test (the Southeastern China Brief Affect Recognition Test). Correlation analyses were conducted between the FEPR deficits and cognitive functions.

      Results

      Compared with NC, all three groups of AIS patients reported significant FEPR deficits. Although no statistical difference in FEPR deficits were observed among the LBD, RBD and IBD patients, the deficit patterns were markedly different. FEPR deficits were positively correlated with cognitive impairment.

      Conclusions

      FEPR deficits may occur in AIS patients and are associated with impaired cognitive functions, where the cerebral hemispheres and the infratentorial brain are jointly involved. Early recognition and early intervention of FEPR deficits in AIS patients are critical for post-stroke rehabilitation, reconstruction of social function and improvement in life quality.

      Abbreviations:

      FEPR (facial emotion perception and recognition), AIS (acute ischemic stroke), MRI (magnetic resonance imaging), NC (normal control), LBD (left brain damage), RBD (right brain damage), IBD (infratentorial brain damage), MMSE (the Chinese version Mini-Mental State Examination), MoCA (the Beijing version Montreal Cognitive Assessment), ACE-R (the Addenbrooke’s Cognitive Examination-Revised), SCBART (the Southeastern China Brief Affect Recognition Test), SCFEE (Southeastern China Facial Expressions of Emotion), SCNeuF (Southeastern China Neutral Faces), ANOVA (the analysis of variance), LSD (the least-significant difference), ANCOVA (the analysis of covariance)

      Keywords

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