Highlights
- •Cytotoxic lesions of the corpus callosum (CLOCCs) can manifest in a wide variety of systemic infections including Coxiella Burnetii.
- •CLOCCs, in rare cases, also manifest in response to seizure activity, medications, haemorrhage, neoplasm and metabolic disturbance.
- •Differentials for CLOCCs include Marchiafava-Bignami disease, stroke, lymphoma and glioblastoma.
Abbreviations:
CLOCC (Cytotoxic lesion of the Corpus Callosum), FLAIR (FLuid Attenuated Inverse Recovery), DWI (Diffusion weighted Imaging), ADC (Apparent Diffusion Coefficient)To read this article in full you will need to make a payment
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References
- Cytotoxic Lesions of the Corpus Callosum That Show Restricted Diffusion: Mechanisms, Causes, and Manifestations.RadioGraphics. 2017; 37: 562-576
- COVID-19-Associated Cytotoxic Lesions of the Corpus Callosum.AJNR Am J Neuroradiol. 2020; 41: 1905-1907
Bulakbasi N, Kocaoglu M, Tayfun C, Ucoz T. Transient Splenial Lesion of the Corpus Callosum in Clinically Mild Influenza-Associated Encephalitis/Encephalopathy. Am J Neuroradiol 2006;27(9):1983–1986.
- Acute cerebellitis caused by Coxiella burnetii.Ann Neurol. 1999; 45: 124-127
- Neurological Involvement in Acute Q Fever: A Report of 29 Cases and Review of the Literature.Arch Intern Med. 2002; 162: 693
Article info
Publication history
Accepted:
August 3,
2022
Received:
June 20,
2022
Identification
Copyright
© 2022 Elsevier Ltd. All rights reserved.
