Adult-onset Alexander disease mimicking multiple system atrophy predominant cerebellar ataxia


      • We report a patient with adult-onset Alexander disease (AOAD) mimicking MSA-C.
      • Cerebellar ataxia, spasticity, bradykinesia and urinary disturbance were observed.
      • The patient showed striatal dopaminergic deficit on DAT SPECT.
      • We should recognize that AOAD can affect striatal dopaminergic systems.


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