Highlights
- •The management of COVID-19 patients who suffer from stroke poses a challenge to healthcare professionals.
- •There are no specific clinical guidelines established in handling COVID-19 positive patients who are eligible for thrombolysis.
- •There is a probable relationship of COVID-19 and Stroke and effective monitoring is warranted.
Abstract
Keywords
1. Introduction
- Zhou Fei
- Yu Ting
- Du Ronghui
- Fan Guohui
- Liu Ying
- Liu Zhibo
- et al.
Department of Health, Updates on novel coronavirus disease (COVID-19). Retrieved from https://www.doh.gov.ph/2019-nCov; 2020 Manila, Philippines.
2. Case report


TEST | SCORE | Reference range |
---|---|---|
WBC | 13,200 | 4800–10,800 mm3 |
Lymphocyte count | 11% | 19–48% |
Platelet count | 409,000 | 150,000–400,000/mm3 |
Creatinine | 0.69 | 0.55–1.02 mg/dL |
Lactate Dehydrogenase | 406 | 85–227 U/L |
Highly-sensitive cardiac troponin I | 14.5 | <11 ng/dL |
Prothrombin time | 12.9 | 11.9–14.2 s |
CRP | 192 | <6 mg/dL |
ESR | 86 | 0–30 mm/hr |
Procalcitonin | 0.80 | <0.5 ng/ml – low risk for sepsis >2.0 ng/ml – High risk for severe sepsis or septic shock |
D-Dimer | 1160 | 0–246 ng/ml |
Serum ferritin | 4609.33 | 4.63–204 ng/ml |
Albumin | 2.3 | g/dL |
ALT | 34 | 14–59 U/L |
AST | 25 | 15–37 U/L |
Imaging features | ||
Consolidation | Present | |
Ground-glass opacity | Present | |
Bilateral pulmonary infiltration | Present |
3. Discussion
Rodriguez-Morales Alfonso J, Cardona-Ospina Jaime A, Gutiérrez-Ocampo Estefanía, Villamizar-Peña Rhuvi, Holguin-Rivera Yeimer, Escalera-Antezana Juan Pablo, et al. On behalf of the Latin American network of coronavirus disease 2019-COVID-19 research (LANCOVID-19). Travel Med Infect Dis https://doi.org/10.1016/j.tmaid.2020.101623.
- Zhou Fei
- Yu Ting
- Du Ronghui
- Fan Guohui
- Liu Ying
- Liu Zhibo
- et al.
Rodriguez-Morales Alfonso J, Cardona-Ospina Jaime A, Gutiérrez-Ocampo Estefanía, Villamizar-Peña Rhuvi, Holguin-Rivera Yeimer, Escalera-Antezana Juan Pablo, et al. On behalf of the Latin American network of coronavirus disease 2019-COVID-19 research (LANCOVID-19). Travel Med Infect Dis https://doi.org/10.1016/j.tmaid.2020.101623.
- Zhou Fei
- Yu Ting
- Du Ronghui
- Fan Guohui
- Liu Ying
- Liu Zhibo
- et al.
Rodriguez-Morales Alfonso J, Cardona-Ospina Jaime A, Gutiérrez-Ocampo Estefanía, Villamizar-Peña Rhuvi, Holguin-Rivera Yeimer, Escalera-Antezana Juan Pablo, et al. On behalf of the Latin American network of coronavirus disease 2019-COVID-19 research (LANCOVID-19). Travel Med Infect Dis https://doi.org/10.1016/j.tmaid.2020.101623.
4. Conclusion
Acknowledgements
References
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.Lancet. 2020; https://doi.org/10.1016/S0140-6736(20)30566-3
- A report about coronavirus disease 2019 (COVID-19).(Retrieved from)2020
- Laboratory-confirmed respiratory infections as triggers for acute myocardial infarction and stroke: a self-controlled case series analysis of national linked datasets from Scotland.Eur Respir J. 2018; 51: 1701794https://doi.org/10.1183/13993003.01794-2017
- Intravenous alteplase for stroke beyond the guidelines and in particular clinical situations.Stroke AHA. 2007; 38: 2612-2618https://doi.org/10.1161/STROKEAHA.106.480566
Elkind Mitchell SV, Harrington Robert A, Benjamin Ivor J. Role of the American Heart Association in the global COVID-19 pandemic. DOI: 10.1161/CIRCULATIONAHA.120.046749.
Huang Yihui, Tu Mengqi, Wang Shipei, Chen Sichao, Zhou Wei, Chen Danyang, et al. Travel medicine and infectious disease. https://doi.org/10.1016/j.tmaid.2020.101606.
Rodriguez-Morales Alfonso J, Cardona-Ospina Jaime A, Gutiérrez-Ocampo Estefanía, Villamizar-Peña Rhuvi, Holguin-Rivera Yeimer, Escalera-Antezana Juan Pablo, et al. On behalf of the Latin American network of coronavirus disease 2019-COVID-19 research (LANCOVID-19). Travel Med Infect Dis https://doi.org/10.1016/j.tmaid.2020.101623.
Department of Health, Updates on novel coronavirus disease (COVID-19). Retrieved from https://www.doh.gov.ph/2019-nCov; 2020 Manila, Philippines.
- First case of COVID-19 infection with fulminant myocarditis complication: case report and insights.Preprints. 2020; : 2020030180https://doi.org/10.20944/preprints202003.0180.v1
- Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies.J Biol Regul Homeost Agents. 2020; 34 (pii: 1. doi: 10.23812)
- J Neurol Res North Am. 2016; (The role of D-dimer, fibrinogen and C-reactive protein as plasma biomarkers in acute ischemic stroke) (Available at: https://www.neurores.org/index.php/neurores/article/view/362/346 [Date accessed: 23 Mar. 2020])
- Erythrocyte sedimentation rate: can be a prognostic marker in acute ischemic stroke?.Turk J Cerebrovasc Dis. 2013; 19: 18-22https://doi.org/10.5505/tbdhd.2013.32042
- Inflammatory responses and inflammation-associated diseases in organs.Oncotarget. 2017; 9: 7204-7218https://doi.org/10.18632/oncotarget.23208