Highlights
- •Refractory cluster headache (CH) secondary to a macroprolactinoma is a rare entity.
- •Medical treatment with dopamine agonists allowed for permanent recovery.
- •Measurement of prolactin levels and MRI might be considered in these patients.
Abstract
While headache is not an uncommon symptom in patients suffering from pituitary adenomas,
cluster headache (CH) has rarely been reported in such cases. Headache associated
with hyperprolactinemia has been reported to be responsive to dopamine agonists (DA
agonists) in many patients. We report on a patient with refractory CH secondary to
a macroprolactinoma who showed immediate and permanent clinical and radiologic recovery
following medical treatment with DA agonists. Measurement of prolactin levels in addition
to cranial magnetic resonance imaging might be considered in patients with refractory
CH, until the significance of this potential causality becomes clearer.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of Clinical NeuroscienceAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Clinical characteristics and risk factors for headache associated with non-functioning pituitary adenomas.Cephalalgia. 2016;
- The clinical characteristics of headache in patients with pituitary tumours.Brain. 2005; 128: 1921-1930
- Cluster headache: pathogenesis, diagnosis, and management.Lancet. 2005; 366: 843-855
- Long-term outcomes and clinical characteristics of hypnic headache syndrome: 40 patients series from a tertiary referral center.Headache. 2016; 56: 717-724
Article info
Publication history
Published online: February 10, 2017
Accepted:
January 25,
2017
Received:
November 2,
2016
Identification
Copyright
© 2017 Elsevier Ltd. All rights reserved.
