Highlights
- •Rapid eye movement sleep behavior disorder (RBD) is common in Parkinson’s disease (PD).
- •Women with PD and RBD have less aggressive dream enacting behaviour.
- •Anxiety and depression is more common.
Abstract
Rapid eye movement sleep behavior disorder (RBD) is common in Parkinson’s disease
(PD). Little information exists about RBD in women with PD. The aim of this study
was to determine the clinical expression of RBD in women with PD and note any differences
in women with PD with and without RBD. One hundred fifty-six patients with PD were
recruited. There were 37 women with PD and probable RBD was diagnosed using the RBD
Screening Questionnaire. Other scales included Pittsburgh Sleep Quality Index, Parkinson’s
Disease Sleep Scale, Epworth Sleep Scale, Hamilton Anxiety Rating Scale and Hamilton
Depression Rating Scale. Probable RBD was diagnosed in 10 women with PD (27%). Most
often (70%) RBD occurred after the onset of parkinsonian symptoms. Women with probable
RBD were older, had shorter duration of PD symptoms, lower tremor score, and higher
axial signs score. They had insomnia (80% versus non-probable RBD patients 44%, p = 0.019), and poor sleep quality with excessive daytime sleepiness. Anxiety and depression
were common in women with probable RBD. Episodes were brief and confined to vocalization
and simple limb movements. No injury to self or bed partners was noted. Women with
PD have fewer fights and less aggressive dream enacting behaviour than men, but suffer
from significant disturbed sleep, and levels of anxiety and depression.
Keywords
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Article info
Publication history
Published online: January 04, 2016
Accepted:
August 30,
2015
Received:
August 24,
2014
Identification
Copyright
© 2015 Elsevier Ltd. All rights reserved.
