Abstract
Spinal epidural lipomatosis (SEL) is an abnormal accumulation of unencapsulated, epidural
fat. SEL can be divided into idiopathic and secondary. Secondary SEL is often associated
with chronic steroid use and endocrinopathies. Idiopathic SEL has been associated
with obesity. SEL has been implicated in a variety of neurologic impairments and surgical
decompression has been shown to prevent further worsening or result in improvement.
We report a 53-year-old man with obesity and a history of chronic back pain who developed
idiopathic SEL diagnosed by MRI, which subsequently resolved completely over an 8 month follow-up period. To our knowledge, this is the first reported case of complete
radiographic resolution of SEL without any treatment.
Keywords
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References
- Spinal cord compression by extradural fat after renal transplantation.Med J Aust. 1975; 1: 201-203
- Spinal epidural lipomatosis: report of a case secondary to hypothyroidism and review of literature.J Neurol. 1987; 234: 172-176
- Spinal epidural lipomatosis: a review of its causes and recommendations for treatment.Neurosurg Focus. 2004; 16: E11
- Symptomatic spinal epidural lipomatosis in a patient with Cushing’s disease.Neurology. 1995; 45: 2281-2283
- Symptomatic spinal epidural lipomatosis after local epidural corticosteroid injections: case report.Neurosurgery. 1999; 45: 162-165
- Symptomatic spinal epidural lipomatosis associated with Cushing’s syndrome.Neurosurgery. 1981; 8: 724-727
- Epidural lipomatosis complicating lumbar steroid injections.J Spinal Disord. 1999; 12: 526-529
- Lumbosacral epidural lipomatosis: MRI grading.Eur Radiol. 2003; 13: 1709-1721
- Symptomatic epidural lipomatosis secondary to obesity. Case report.J Neurosurg. 1996; 85: 348-350
- Epidural lipomatosis in steroid-treated patients.Spine (Phila Pa 1976). 1992; 17: 183-188
- Spinal epidural lipomatosis due to a bronchial ACTH-secreting carcinoid tumour.J Clin Neurosci. 2010; 17: 1461-1462
- Spinal epidural lipomatosis: case reports, literature review and meta-analysis.Spine J. 2005; 5: 202-211
- Decompression of idiopathic lumbar epidural lipomatosis: diagnostic magnetic resonance imaging evaluation and review of the literature.J Neurosurg Spine. 2006; 4: 24-30
- Idiopathic spinal epidural lipomatosis.Neurosurgery. 1997; 41 ([discussion 74–65]): 68-74
- Twisted tail: spinal epidural lipomatosis responding to chemotherapy in a patient with non-small-cell lung cancer.J Med Imaging Radiat Oncol. 2008; 52: 525-526
- Is epidural lipomatosis associated with abnormality of body fat distribution? A case report.Eur Spine J. 2006; 15: 105-108
- Spinal epidural lipomatosis – a brief review.J Clin Neurosci. 2008; 15: 1323-1326
- Symptomatic deposition of epidural fat in a morbidly obese woman.AJNR Am J Neuroradiol. 1982; 3: 664-665
- Idiopathic and glucocorticoid-induced spinal epidural lipomatosis.J Neurosurg. 1991; 74: 38-42
- Cauda equina compression by epidural lipomatosis in obesity. Effectiveness of weight reduction.J Rheumatol. 1995; 22: 1771-1775
- Epidural lipomatosis. Interest of magnetic resonance imaging in a weight-reduction treated case.Spine (Phila Pa 1976). 1994; 19: 251-254
- Idiopathic symptomatic epidural lipomatosis of the lumbar spine.Acta Neurochir (Wien). 2003; 145 ([discussion 321]): 315-320
Article info
Publication history
Accepted:
September 27,
2012
Received:
September 23,
2012
Identification
Copyright
© 2013 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.