Abstract
Inferior alveolar nerve blocks are commonly performed for dental anaesthesia. The
procedure is generally safe with a low rate of complications. We report a patient
with a reproducible, delayed-onset sensory deficit associated with contrast-enhancing
lesions in the trigeminal nerve, pons and medulla following inferior alveolar nerve
local anaesthesia. We propose that this previously undescribed condition is a form
of Type IV hypersensitivity reaction.
Keywords
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References
- Severe adverse reactions to dental local anaesthetics: prolonged mandibular and lingual nerve anaesthesia.Aust Dent J. 2011; 56: 154-159
- Trigeminal nerve injury associated with injection of local anesthetics: needle lesion or neurotoxicity?.J Am Dent Assoc. 2011; 142: 531-539
- Delayed-type hypersensitivity (type IV) reactions in dental anesthesia.Allergy Asthma Proc. 2007; 28: 477-479
- Severe adverse reactions to dental local anaesthetics: systemic reactions.Aust Dent J. 2011; 56: 148-153
- An unusual delayed complication of inferior alveolar nerve block.Br J Oral Maxillofac Surg. 2010; 48: 51-52
- Mitigation of direct neurotoxic effects of lidocaine and amitriptyline by inhibition of p38 mitogen-activated protein kinase in vitro and in vivo.Anesthesiology. 2006; 104: 1266-1273
- Distribution and absorption of local anesthetics in inferior alveolar nerve block: evaluation by magnetic resonance imaging.J Oral Maxillofac Surg. 2011; 69: 2722-2730
- A critical review of local anesthetic sensitivity.Clin Rev Allergy Immunol. 2007; 32: 119-128
- Peripheral facial nerve paralysis after upper third molar extraction.J Craniofac Surg. 2010; 21: 1825-1827
- Facial palsy following dental extraction: report of 2 cases.J Oral Maxillofac Surg. 2003; 61: 840-844
- Reactivation of varicella-zoster virus in delayed facial palsy after dental treatment and oro-facial surgery.J Med Virol. 2000; 62: 42-45
Article info
Publication history
Accepted:
October 6,
2012
Received:
August 16,
2012
Identification
Copyright
© 2013 Published by Elsevier Inc.
