Advertisement

Ischaemic stroke provoked by sexual intercourse

      Abstract

      The association between long term risk factors and stroke has been well established, but very little is known about factors that may precipitate acute stroke. We describe two young women presenting with ischaemic stroke triggered by sexual intercourse. Patient 1 presented with a cardioembolic stroke probably secondary to the interaction between a patent foramen ovale and thrombophilic abnormalities; Patient 2, presenting with orgasmic headache, had a cryptogenic striatocapsular infarct. Sexual intercourse should be considered as an unusual, but possible, trigger of cerebral ischaemia, especially in young patients presenting with cryptogenic stroke.

      Keywords

      To read this article in full you will need to make a payment

      Subscribe:

      Subscribe to Journal of Clinical Neuroscience
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Koton S.
        • Tanne D.
        • Bornstein N.M.
        • et al.
        Triggering risk factors for ischemic stroke: a case-crossover study.
        Neurology. 2004; 63: 2006-2010
        • Pandian J.D.
        • Perel R.
        • Henderson R.D.
        • et al.
        Unusual triggers for stroke.
        J Clin Neurosci. 2007; 14: 786-787
        • Becker K.
        • Skalabrin E.
        • Hallam D.
        • et al.
        Ischemic stroke during sexual intercourse: a report of 4 cases in persons with patent foramen ovale.
        Arch Neurol. 2004; 61: 1114-1116
        • Velicu S.
        • Biller J.
        • Hacein-Bey L.
        • et al.
        Paradoxical embolism to the central nervous system after sexual intercourse in a young woman with a complex atrial septal abnormality.
        J Stroke Cerebrovasc Dis. 2008; 17: 320-324
        • Lee S.J.
        • Kim J.S.
        • Lee K.S.
        • et al.
        Coital transient ischaemic attacks.
        Eur J Neurol. 2008; 15: e101-e102
        • Di Tullio M.R.
        • Sacco R.L.
        • Sciacca R.R.
        • et al.
        Patent foramen ovale and the risk of ischemic stroke in a multiethnic population.
        J Am Coll Cardiol. 2007; 49: 797-802
        • Handke M.
        • Harloff A.
        • Bode C.
        • et al.
        Patent foramen ovale and cryptogenic stroke: a matter of age?.
        Semin Thromb Hemost. 2009; 35: 505-514
        • Pezzini A.
        • Grassi M.
        • Zotto E.D.
        • et al.
        Do common prothrombotic mutations influence the risk of cerebral ischaemia in patients with patent foramen ovale? Systematic review and meta-analysis.
        Thromb Haemost. 2009; 101: 813-817
        • Matarin M.
        • Singleton A.
        • Hardy J.
        • et al.
        The genetics of ischaemic stroke.
        J Intern Med. 2010; 267: 139-155
        • Casas J.P.
        • Hingorani A.D.
        • Bautista L.E.
        • et al.
        Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.
        Arch Neurol. 2004; 61: 1652-1661
        • Calabrò R.S.
        • Gervasi G.
        • Bramanti P.
        Can interaction between atrial septal abnormalities and genetic prothrombotic polymorphisms play a role in cryptogenic ischemic stroke? Description of a family.
        Neurol Sci. 2012; 33: 117-119
        • Yeh Y.C.
        • Fuh J.L.
        • Chen S.P.
        • et al.
        Clinical features, imaging findings and outcomes of headache associated with sexual activity.
        Cephalalgia. 2010; 30: 1329-1335
        • Ben Shlomo Y.
        • McCarron P.
        • Frankel S.
        • et al.
        Sexual intercourse and risk of ischaemic stroke and coronary heart disease: the Caerphilly study.
        J Epidemiol Community Health. 2002; 56: 99-102