Abstract
The aim of this retrospective study was to investigate the effect of adjuvant hyperbaric
oxygen (HBO) therapy on the duration of antibiotic treatment and rate of radiological
improvement in the management of spinal tuberculosis. We reviewed a total of 51 patients
with tuberculous spondylitis of the spine who were treated by percutaneous abscess
drainage or radical surgical debridement with chemotherapy, and of whom 16 randomly
selected patients also received adjuvant HBO therapy and 35 did not. Serological markers
were monitored in the course of treatment. Percutaneous needle biopsy was performed
on each patient before treatment. Spine and chest radiographs, CT scans and MRI were
performed. Infection control was achieved in all patients and no recurrence occured.
To our knowledge this is the first reported series of patients with spinal tuberculosis
treated with HBO therapy as an adjunct to antituberculous chemotherapy. This combination
provided earlier clinical and radiologic improvement than chemotherapy alone.
Keywords
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Article info
Publication history
Accepted:
February 20,
2009
Received:
August 18,
2008
Identification
Copyright
© 2009 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.
