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Case Report| Volume 16, ISSUE 12, P1658-1660, December 2009

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Skull osteohypertrophy as a complication of bone wax

  • Tomoya Kamide
    Affiliations
    Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641, Japan
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  • Mitsutoshi Nakada
    Correspondence
    Corresponding author. Tel.: +81 76 265 2384; fax: +81 76 234 4262.
    Affiliations
    Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641, Japan
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  • Yuichi Hirota
    Affiliations
    Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641, Japan
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  • Yutaka Hayashi
    Affiliations
    Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641, Japan
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  • Yasuhiko Hayashi
    Affiliations
    Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641, Japan
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  • Naoyuki Uchiyama
    Affiliations
    Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641, Japan
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  • Jun-ichiro Hamada
    Affiliations
    Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641, Japan
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      Abstract

      A 51-year-old woman with bone wax–induced osteohypertrophy presented with exophthalmos 9 years after a craniotomy for a right internal carotid bifurcation aneurysm. CT scans revealed thickening of the frontotemporal bone flap and surrounding bone, thickening of the upper and lateral orbital walls, and a limited intraorbital cavity. Intraoperative findings revealed residual bone wax under the bone flap, grayish-white discoloration of the flap, and degeneration of the temporal muscle. Pathological examination revealed granulation and osteogenesis due to a foreign body. To our knowledge, this is the first report of bone wax–induced hyperostosis leading to exophthalmos.

      Keywords

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      References

        • Alberius P.
        • Klinge B.
        • Sjogren S.
        Effects of bone wax on rabbit cranial bone lesions.
        J Craniomaxillofac Surg. 1987; 15: 63-67
        • Allison R.T.
        Foreign body reactions and an associated histological artifact due to bone wax.
        Br J Biomed Sci. 1994; 51: 14-17
        • Aurelio J.
        • Chenail B.
        • Gerstein H.
        Foreign-body reaction to bone wax. Report of a case.
        Oral Surg Oral Med Oral Pathol. 1984; 58: 98-100
        • Gibbs L.
        • Kakis A.
        • Weinstein P.
        • et al.
        Bone wax as a risk factor for surgical site infection following neurospinal surgery.
        Infect Control Hosp Epidemiol. 2004; 25: 346-348
        • Johnson P.
        • Fromm D.
        Effects of bone wax on bacterial clearance.
        Surgery. 1981; 89: 206-209
        • Lavigne M.
        • Boddu Siva Rama K.R.
        • Doyon J.
        • et al.
        Bone-wax granuloma after femoral neck osteoplasty.
        Can J Surg. 2008; 51: 58-60
        • Patel R.B.
        • Kwartler J.A.
        • Hodosh R.M.
        Bone wax as a cause of foreign body granuloma in the cerebellopontine angle. Case illustration.
        J Neurosurg. 2000; 92: 362
        • Sorrenti S.J.
        • Cumming W.J.
        • Miller D.
        Reaction of the human tibia to bone wax.
        Clin Orthop. 1984; 182: 293-296
        • Julsrud M.E.
        A surgical complication: allergic reaction to bone wax.
        J Foot Surg. 1980; 19: 152-154
        • Katz S.E.
        • Rootmann J.
        Adverse effects of bone wax in surgery of the orbit.
        Ophthal Plast Reconstr Surg. 1996; 12: 121-126
        • Tay H.L.
        • Tan L.K.S.
        Surgical bone wax causing epistaxis.
        J Laryngol Otol. 1996; 110: 267-268
        • Verborgt O.
        • Verellen K.
        • Thielen F.V.
        • et al.
        A retroperitoneal tumor as a late complication of the use of bone wax.
        Acta Orthop Belg. 2000; 66: 389-391
        • Tehranzadeh J.
        • Fung Y.
        • Donohue M.
        • et al.
        Computed tomography of Paget disease of the skull versus fibrous dysplasia.
        Skeletal Radiol. 1998; 27: 664-672
        • Wagner P.H.
        • Heilmann P.
        • Schulz A.
        • et al.
        Fibrous dysplasia: differential diagnosis from Paget’s disease.
        Dtsch Med Wochenschr. 2002; 127: 2264-2268
        • Anfinsen O.G.
        • Sudmann B.
        • Rait M.
        • et al.
        Complications secondary to the use of standard bone wax in seven patients.
        J Foot Ankle Surg. 1993; 32: 505-508