Abstract
We describe a 76-year-old woman who presented with painful muscle weakness and numbness
in both legs secondary to grossly ossified meningiomas at the T8 and T11–T12 vertebral
levels. Midline durotomy followed by en bloc excision of the tumours, together with partial resection of the dura mater and the
arachnoid, was performed. Histopathological examination showed both tumours consisted
of three different histological patterns: psammomatous, fibrous, and metaplastic subtypes.
Immunostaining for bone morphogenetic protein-2 and vascular endothelial growth factor
was significantly positive in the areas surrounding mature bone tissues in the metaplastic
and psammomatous subtypes.
Keywords
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Article info
Publication history
Accepted:
March 19,
2009
Received:
December 17,
2008
Identification
Copyright
© 2009 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.
