Abstract
Meningiomas and breast cancers are common tumors among women in the fifth to seventh
decade. However, metastasis from breast cancer to an intracranial meningioma is rare.
A 63-year-old woman presented with headache, nausea and vomiting, and progressive
right hemiparesis for one month. She had undergone a right modified radical mastectomy
in another hospital 10 years prior. At that time, the pathological diagnosis was infiltrating
ductal carcinoma. She required adjuvant radiotherapy and chemotherapy for a local
recurrence 7 years later. On admission to our hospital, cranial CT scans showed a
brightly enhancing, irregularly shaped lesion over the left high parietal lobe with
surrounding parenchymal edema. Histopathological examination of the lesion revealed
two distinct tumor types, meningioma and metastatic carcinoma of breast tissue origin.
Although meningiomas have well-known radiological features, other tumors, including
metastases from breast cancers may simulate them. In the clinical setting of previously
diagnosed breast cancer, prompt craniotomy for removal of meningioma-like intracranial
lesions is recommended to avoid missing the diagnosis of breast cancer metastasis
which carries a poorer prognosis than meningioma and requires a different treatment
strategy.
Keywords
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References
- Association of breast cancer with meningioma.Eur J Surg Oncol. 1998; 24: 332-334
- Meningiomas associated with brain metastases.Zentralbl Neurochir. 2002; 63: 111-115
- Metastasis of breast carcinoma to intracranial meningioma. Case report and review of the literature.J Neurosurg Sci. 1992; 36: 169-172
- Metastasis of breast carcinoma to intracranial meningioma.J Neurosurg Sci. 2004; 48: 71-73
- Tumor in tumor: metastasis of breast carcinoma to intracranial meningioma.Tumori. 2001; 87: 423-427
- Metastasis of breast cancer to intracranial meningioma: case report.Am J Clin Oncol. 2002; 4: 414-417
- Breast carcinoma metastatic to a meningioma.Arch Intern Med. 1989; 149: 959-962
- Intrameningioma metastasis as first clinical manifestation of occult primary breast carcinoma.Neurosurg Rev. 2006; 29: 49-54
- Metastasis of prostatic carcinoma to intracranial meningioma. Case report.J Neurosurg. 1983; 58: 774-777
- Ûber Karzinommetastase in einem Duraendotheliom.Zentralbl Allg Pathol. 1933; 58: 1633-1666
- Metastasis of invasive carcinoma of the breast to an extradural meningioma of the cranial vault.Cancer. 1987; 60: 1081-1084
- Metastatic carcinoma in meningioma.South Med J. 1976; 69: 514-517
- Association of breast cancer with meningioma: report of a case and review of the literature.Jpn J Clin Oncol. 2001; 31: 510-513
- Neoplasm to neoplasm metastasis. An acidophil adenoma harbouring metastaic carcinoma: a case report.Arch Pathol. 1971; 91: 135-139
- Metastatic carcinoma in a meningioma.J Neurosurg. 1963; 20: 892-894
- Metastasis of breast carcinoma to an intracerebral oligodendroglioma.Zentralbl Neurochir. 1965; 25: 206-209
- Incidence and clinicopathologic features of meningioma.J Neurosurg. 1989; 71: 665-672
- Nervous system neoplasms and primary malignancies of other sites.Neurology. 1975; 25: 705-712
- Metastases of carcinoma to intracranial meningioma: report of two cases and review of the literature.Cancer. 1981; 48: 2668-2673
- Malignant carcinoid tumor metastatic to a meningioma.Cancer. 1981; 47: 1872-1877
- Presence of sex steroid hormone receptors in meningioma tissue.Surg Neurol. 1981; 15: 415-418
- Metastasis of breast carcinoma to intracranial meningioma. Case report.Neurosurg Rev. 1994; 17: 233-236
- Case report: metastasis of carcinoma of prostate to meningioma.Virchows Arch Pathol Anat. 1975; 366: 87-91
- Metastases of cancer to cancer.Cancer. 1968; 22: 635-643
- Carcinoma metastasis to meningioma.J Neurol Neurosurg Psychiatry. 1984; 47: 561-563
- Metastasis of breast cancer to a meningioma.Arch Anat Cytol Pathol. 1978; 26: 175-176
- Metastases to meningioma.Am J Neuroradiol. 1998; 19: 1120-1122
- Lung carcinoma presenting as metastasis to intracranial meningioma: case report and review of the literature.Am J Clin Oncol. 1999; 22: 199-202
Article info
Publication history
Accepted:
February 3,
2009
Received:
October 5,
2008
Identification
Copyright
© 2009 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.
