Abstract
This report documents changes to axonal excitability in motor nerves in acute camphor
toxicity. Although there were no changes to indicate an alteration in resting membrane
potential, there was an exaggerated response to hyperpolarising currents in both threshold
electrotonus and the current–threshold relationship. These findings suggest a transient
decrease in the hyperpolarisation-activated conductance (IH). This report demonstrates that recently developed techniques for measuring axonal
excitability are readily applied in the acute care setting and can document subclinical
abnormalities that could be relevant to the underlying pathophysiology.
Keywords
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Article info
Publication history
Accepted:
January 21,
2009
Received:
September 9,
2008
Identification
Copyright
© 2009 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.
