Summary
Autosomal dominant polycystic kidney disease (ADPKD) is a generalized disease known
to be associated with intracranial aneurysms. Non-aneurysmal intracerebral hemorrhage
(ICH) has also been reported in ADPKD. We report a familial clustering of ICH and
symptomatic ADPKD. This pedigree had at least six affected family members who suffered
from ADPKD, hypertension and non-aneurysmal ICH. The proband demonstrated ADPKD, hypertension
and cerebral hemorrhage. To our knowledge, this is the first report of familial ICH
in ADPKD, which may have underlying genetic and environmental etiologies.
Keywords
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Article info
Publication history
Accepted:
May 31,
2004
Received:
October 3,
2003
Identification
Copyright
© 2005 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.
