Summary
Transcranial magnetic stimulation was used to map hand muscle representations in the
motor cortex of a patient in whom infarction of the sensory thalamus deprived the
sensorimotor cortex of sensory input. The threshold for activation of the motor cortex
on the affected side was higher and the cortical representational maps of individual
muscles were less well defined than those on the normal side. It is concluded that
electrophysiological changes in cortical organisation can be demonstrated following
withdrawal of, or imbalance in sensory afferent activity to the cerebral cortex in
humans.
Keywords
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Article info
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Copyright
© 2005 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.