This paper is only available as a PDF. To read, Please Download here.
Abstract
Non-neoplastic demyelinating processes of the brain with ring enhancing lesions and
mass effect on MRI imaging, mimicking malignant brain tumours, are rare phenomena.
We document the case of a 32 year old male with clinical, radiological and initial
histological findings, suggestive of a malignant brain tumour. Additional investigations
confirmed the diagnosis of multiple sclerosis.
This case is significant as the lesion could not be easily distinguished from a malignant
brain tumour on imaging alone. Cases such as this illustrate the importance of considering
a demyelinating process in the differential diagnosis of tumour-like brain lesions.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of Clinical NeuroscienceAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Childhood multiple sclerosis: Clinical features and demonstration of changes in T-cell subsets with disease activity.Ann Neurol. 1982; 11: 463-468
- Multiple sclerosis plaque mimicking tumour on computer tomography.Br Med J. 1982; 285: 1616-1617
- A Multiple sclerosis: Large plaque causing mass effect on and ring sign.J Comput Assist Tomogr. 1981; 5: 892-894
- Cranial CT in multiple sclerosis showing a mass effect.Surg Neurol. 1979; 12: 307-310
- Multiple sclerosis mimicking primary brain tumor.Arch Pathol Lab Med. 1987; 111: 468-646
- J Neurosurg. 1981; 55: 620-623
- Proton MR spectroscopy and MR imaging in acute and chronic multiple sclerosis-ring like appearances in acute plaques.Acta Radiol. 1996; 37: 278-287
- Cerebral CT lesions in multiple sclerosis mimicking multiple metastases.J Neurol Neurosurg Psychiatry. 1991; 54: 92
Kasahata, N, Murayama, S, Shiota, J, A clinico-pathological study of so-called “acute multiple sclerosis” mimicking a brain tumour on the MRI findings Rinsho Shinkeigaku, 1999, 39, 327, 332
- Glioblastoma and malignant astrocytoma.in: Kaye AH Jaws Jr, AR Brain Tumors. 1995: 446-447
- Multiple primary neoplasms and the nervous system.Cancer. 1977; 4: 1961-1967
- Development of multiple lesions during radiation therapy and chemotherapy in patients with gliomas.J Neurosurg. 1986; 65: 654-658
- Cavernous haemangioma mimicking multiple sclerosis.BMJ. 1999; June 12; 318: 1604-1605
- Primary cerebral lymphoma mimicking multiple sclerosis.Arch Neurol. 1979; 36: 598
- Multicentric malignant glioma.Br J Neurosurg. 1991; 5: 631-634
- Imaging patterns of multifocal gliomas.Eur J Radiol. 1993; 16: 163-170
- Posterior fossa tumor mimicking multiple sclerosis.South Med J. 1974; 67: 1485-1488
- Focal plaque of demyelination mimiking cerebral tumor in a pediatric patient.Pediatr Neurosurg. 1988; 29: 60-63
- Cavernous angioma of brain stem mimiking multiple sclerosis.Folia Neuropathol. 1955; 33: 4
- Cavernous angioma of the brain stem mimicking multiple sclerosis.The New England Journal of Medicine. 1977; 336: 875-876
Article info
Publication history
Accepted:
April 20,
2001
Received:
March 13,
2001
Identification
Copyright
© 2002 Elsevier Science Ltd. Published by Elsevier Inc. All rights reserved.